Medical name: Sildenafil

Viagra, a well-known medication for treating erectile dysfunction (ED), has a medical name: sildenafil. Sildenafil is also used to treat pulmonary arterial hypertension (PAH) in both men and women.

Drug classification: Phosphodiesterase-5 (PDE5) inhibitors

Sildenafil belongs to a class of medications called phosphodiesterase-5 (PDE5) inhibitors. These medicines work by preventing an enzyme called phosphodiesterase type-5 from working too quickly.

Mechanism of action in erectile dysfunction (ED)

In the treatment of erectile dysfunction, sildenafil increases blood flow to the penis during sexual stimulation by relaxing the blood vessels. This helps to cause an erection, improving the symptoms of ED.

Mechanism of action in pulmonary arterial hypertension (PAH)

For pulmonary arterial hypertension, sildenafil works on the PDE5 enzyme in the lungs to relax the blood vessels. This reduces resistance to blood flow and lowers mean pulmonary arterial pressure, improving the symptoms of PAH.

Other brand names: Aronix, Liberize, Nipatra, Revatio, Grandipam

In addition to Viagra, sildenafil is available under other brand names, such as Aronix, Liberize, Nipatra, Revatio, and Grandipam.

Each brand may have specific indications and dosages.

Available dosages: 25 mg, 50 mg, and 100 mg

Sildenafil is available in oral tablet form, with dosages of 25 mg, 50 mg, and 100 mg for the treatment of erectile dysfunction. Most patients receive a prescription for 50 mg of oral sildenafil, taken as needed approximately 1 hour before sexual activity.

Prescription guidelines and dose titration

The dose of sildenafil can be titrated upward to a maximum of 100 mg or downward to 25 mg, depending on the efficacy and tolerability of the medication. It is essential to follow the directions on the prescription label carefully and consult a doctor or pharmacist to explain any part that is not understood.

Important considerations: Following directions and potential drug interactions

It is crucial to inform the doctor about all the medications being taken, even those that do not appear on the list, as they may interact with sildenafil. Proper communication with healthcare providers and adherence to prescription guidelines can help ensure safe and effective use of sildenafil for treating erectile dysfunction and pulmonary arterial hypertension.